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N-Acetyl Selank Amidate is a modified version of Selank, a synthetic peptide with nootropic and neuroprotective properties, and these modifications may enhance its stability, bioavailability, and efficacy.
| Name | N-Acetyl Selank Amidate |
|---|---|
| Sequence | Ac-Thr-Lys-Pro-Arg-Gly-Pro-NH2 |
| CAS No. | / |
| Purity | 99% |
| Appearance | Lyophilized Powder |
| Molecular Formula | C35H62N12O10 |
| Molecular Weight | 800.89 g/mol |
| Storage | Store in an air-tight container away from light at 2-8°C. For best preservation, store below -10°C. |
N-Acetyl Selank Amidate is a modified form of the peptide Selank. Selank is a short nootropic and anxiolytic peptide originally developed in Russia. It is an analogue of naturally occurring tuftsin and has been shown to have immunomodulatory effects.
Research suggests that Selank modifies gene expression in the brain, reducing the effects of the neurotransmitter GABA, altering cell membrane permeability, and enhancing production of brain-derived neurotrophic factor (BDNF).
The modified form of Selank, N-Acetyl Selank Amidate has a longer half-life and greater ability to cross the blood-brain barrier. It also has tighter receptor binding due to the amidation. Selank is currently being researched in animal models for the treatment of stroke and other ischemic brain diseases. It is also under consideration as a treatment of generalized anxiety disorder and to protect memory in the setting of neurodegenerative disease.
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